diff --git a/include/iscsi.h b/include/iscsi.h
index 9cee64b..815664c 100644
--- a/include/iscsi.h
+++ b/include/iscsi.h
@@ -596,6 +596,11 @@ iscsi_synchronizecache10_task(struct iscsi_context *iscsi, int lun,
 				   int immed, iscsi_command_cb cb,
 				   void *private_data);
 EXTERN struct scsi_task *
+iscsi_synchronizecache16_task(struct iscsi_context *iscsi, int lun,
+				   uint64_t lba, uint32_t num_blocks, int syncnv,
+				   int immed, iscsi_command_cb cb,
+				   void *private_data);
+EXTERN struct scsi_task *
 iscsi_prefetch10_task(struct iscsi_context *iscsi, int lun,
 		      uint32_t lba, int num_blocks,
 		      int immed, int group,
@@ -760,6 +765,10 @@ EXTERN struct scsi_task *
 iscsi_synchronizecache10_sync(struct iscsi_context *iscsi, int lun, int lba,
 			      int num_blocks, int syncnv, int immed);
 
+EXTERN struct scsi_task *
+iscsi_synchronizecache16_sync(struct iscsi_context *iscsi, int lun, uint64_t lba,
+			      uint32_t num_blocks, int syncnv, int immed);
+
 EXTERN struct scsi_task *
 iscsi_prefetch10_sync(struct iscsi_context *iscsi, int lun, uint32_t lba,
 		      int num_blocks, int immed, int group);
diff --git a/include/scsi-lowlevel.h b/include/scsi-lowlevel.h
index fe25fbf..d9129f1 100644
--- a/include/scsi-lowlevel.h
+++ b/include/scsi-lowlevel.h
@@ -40,6 +40,7 @@ enum scsi_opcode {
 	SCSI_OPCODE_WRITE16            = 0x8A,
 	SCSI_OPCODE_VERIFY16           = 0x8F,
 	SCSI_OPCODE_PREFETCH16         = 0x90,
+	SCSI_OPCODE_SYNCHRONIZECACHE16 = 0x91,
 	SCSI_OPCODE_WRITE_SAME16       = 0x93,
 	SCSI_OPCODE_SERVICE_ACTION_IN  = 0x9E,
 	SCSI_OPCODE_REPORTLUNS         = 0xA0,
@@ -636,6 +637,8 @@ EXTERN struct scsi_task *scsi_cdb_verify16(uint64_t lba, uint32_t xferlen, int v
 
 EXTERN struct scsi_task *scsi_cdb_synchronizecache10(int lba, int num_blocks,
 			int syncnv, int immed);
+EXTERN struct scsi_task *scsi_cdb_synchronizecache16(uint64_t lba, uint32_t num_blocks,
+			int syncnv, int immed);
 EXTERN struct scsi_task *scsi_cdb_serviceactionin16(enum scsi_service_action_in sa, uint32_t xferlen);
 EXTERN struct scsi_task *scsi_cdb_readcapacity16(void);
 EXTERN struct scsi_task *scsi_cdb_get_lba_status(uint64_t starting_lba, uint32_t alloc_len);
diff --git a/lib/libiscsi.def b/lib/libiscsi.def
index 5604251..0663da9 100644
--- a/lib/libiscsi.def
+++ b/lib/libiscsi.def
@@ -63,6 +63,8 @@ iscsi_set_targetname
 iscsi_set_tcp_keepalive
 iscsi_synchronizecache10_sync
 iscsi_synchronizecache10_task
+iscsi_synchronizecache16_sync
+iscsi_synchronizecache16_task
 iscsi_task_mgmt_abort_task_async
 iscsi_task_mgmt_abort_task_set_async
 iscsi_task_mgmt_async
diff --git a/lib/libiscsi.syms b/lib/libiscsi.syms
index 290545b..f798c00 100644
--- a/lib/libiscsi.syms
+++ b/lib/libiscsi.syms
@@ -61,6 +61,8 @@ iscsi_set_targetname
 iscsi_set_tcp_keepalive
 iscsi_synchronizecache10_sync
 iscsi_synchronizecache10_task
+iscsi_synchronizecache16_sync
+iscsi_synchronizecache16_task
 iscsi_task_mgmt_abort_task_async
 iscsi_task_mgmt_abort_task_set_async
 iscsi_task_mgmt_async
diff --git a/lib/scsi-command.c b/lib/scsi-command.c
index 0e8dfd7..6b39ec7 100644
--- a/lib/scsi-command.c
+++ b/lib/scsi-command.c
@@ -1016,6 +1016,29 @@ iscsi_synchronizecache10_task(struct iscsi_context *iscsi, int lun, int lba,
 	return task;
 }
 
+struct scsi_task *
+iscsi_synchronizecache16_task(struct iscsi_context *iscsi, int lun, uint64_t lba,
+			       uint32_t num_blocks, int syncnv, int immed,
+			       iscsi_command_cb cb, void *private_data)
+{
+	struct scsi_task *task;
+
+	task = scsi_cdb_synchronizecache16(lba, num_blocks, syncnv,
+					   immed);
+	if (task == NULL) {
+		iscsi_set_error(iscsi, "Out-of-memory: Failed to create "
+				"synchronizecache16 cdb.");
+		return NULL;
+	}
+	if (iscsi_scsi_command_async(iscsi, lun, task, cb, NULL,
+				       private_data) != 0) {
+		scsi_free_scsi_task(task);
+		return NULL;
+	}
+
+	return task;
+}
+
 struct scsi_task *
 iscsi_prefetch10_task(struct iscsi_context *iscsi, int lun, uint32_t lba,
 		      int num_blocks, int immed, int group,
diff --git a/lib/scsi-lowlevel.c b/lib/scsi-lowlevel.c
index 87fc509..3f07634 100644
--- a/lib/scsi-lowlevel.c
+++ b/lib/scsi-lowlevel.c
@@ -1459,6 +1459,38 @@ scsi_cdb_synchronizecache10(int lba, int num_blocks, int syncnv, int immed)
 	return task;
 }
 
+/*
+ * SYNCHRONIZECACHE16
+ */
+struct scsi_task *
+scsi_cdb_synchronizecache16(uint64_t lba, uint32_t num_blocks, int syncnv, int immed)
+{
+	struct scsi_task *task;
+
+	task = malloc(sizeof(struct scsi_task));
+	if (task == NULL) {
+		return NULL;
+	}
+
+	memset(task, 0, sizeof(struct scsi_task));
+	task->cdb[0]   = SCSI_OPCODE_SYNCHRONIZECACHE16;
+
+	if (syncnv) {
+		task->cdb[1] |= 0x04;
+	}
+	if (immed) {
+		task->cdb[1] |= 0x02;
+	}
+	*(uint32_t *)&task->cdb[2]  = htonl(lba >> 32);
+	*(uint32_t *)&task->cdb[6]  = htonl(lba & 0xffffffff);
+	*(uint32_t *)&task->cdb[10] = htonl(num_blocks);
+
+	task->cdb_size   = 16;
+	task->xfer_dir   = SCSI_XFER_NONE;
+	task->expxferlen = 0;
+
+	return task;
+}
 
 /*
  * PREFETCH10
diff --git a/lib/sync.c b/lib/sync.c
index c5654cc..ff4366b 100644
--- a/lib/sync.c
+++ b/lib/sync.c
@@ -397,6 +397,27 @@ iscsi_synchronizecache10_sync(struct iscsi_context *iscsi, int lun, int lba,
 	return state.task;
 }
 
+struct scsi_task *
+iscsi_synchronizecache16_sync(struct iscsi_context *iscsi, int lun, uint64_t lba,
+			      uint32_t num_blocks, int syncnv, int immed)
+{
+	struct iscsi_sync_state state;
+
+	memset(&state, 0, sizeof(state));
+
+	if (iscsi_synchronizecache16_task(iscsi, lun, lba, num_blocks,
+					   syncnv, immed,
+					   scsi_sync_cb, &state) == NULL) {
+		iscsi_set_error(iscsi,
+				"Failed to send SynchronizeCache16 command");
+		return NULL;
+	}
+
+	event_loop(iscsi, &state);
+
+	return state.task;
+}
+
 struct scsi_task *
 iscsi_prefetch10_sync(struct iscsi_context *iscsi, int lun, uint32_t lba,
 		      int num_blocks, int immed, int group)